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Current Research Trials

Sydney Retina Clinic and Day Surgery is proud to be associated with a research department named the Sydney Institute of Vision Science. All members of the research team have a strong background in both clinical and laboratory research and are dedicated to the development of new treatment for retinal disease.

In recent months we have been involved in a number of projects, some of which are already completed, and some which are on-going.

Sponsored Trials

Phase 4, open-label, non-randomized, prospective study of OZURDEX® in the Treatment of Diabetic Macular Oedema

Safety and Efficacy of Abicipar Pegol (AGN-150998) in Patients With Neovascular Age-related Macular Degeneration

CENTERA (BAYER BAY86-5321/17514)
A multi-center, single-arm, interventional Phase 4 study to evaluate a Treat and Extend regimen of intravitreal aflibercept for treatment of macular edema secondary to central retinal vein occlusion

SAPPHIRE (CLS1003-301)
A randomized, masked, controlled trial to study the safety and efficacy of suprachoroidal CLS-TA in conjunction with intravitreal aflibercept in subjects with central retinal vein occlusion

IONIS (ISIS 696844-CS3)
A Phase 2, Placebo-Controlled, Double-Masked Study to Assess Safety and Efficacy of ISIS 696844, an Antisense Inhibitor of Complement Factor B, in Patients with Geographic Atrophy Secondary to Age Related Macular Degeneration (AMD)

OPTHEA (OPT-302-1003)
Phase 1b/2a study of OPT-302 in combination with aflibercept for persistent central-involved diabetic macular edema

Upcoming Trials



Investigator Initiated Studies

Clinicopathological Correlation in Macular Degeneration.

Intravitreal Aflibercept for the treatment of treatment resistant retinal vein occlusions.