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Showing 20 Articles

Treatments

Yag Capsulotomy

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Laser Retinopexy

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Vitrectomy

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Eye Conditions

Retinitis Pigmentosa (RP)

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Retinal Tear and Detachment

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Retinal Vein Occlusion

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Macular Hole

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Epiretinal Membrane

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Diabetic retinopathy

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Cystoid Macular Oedema

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Charles Bonnet Syndrome (CBS)

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Central Serous Retinopathy (CSR)

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Cataracts

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Age related macular degeneration

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Eye Health & Wellbeing

Useful Links

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Useful Tools: Lifestyle and Eye Health

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Showing 131 Articles

2022
Current Research Trials

DONOR EYE

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2022
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BEOVU

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2022
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XTEND

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2022
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SCD411-CP101

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2022
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Ripple

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2022
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Rhone-X

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2022
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Pykus

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2022
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Pulsar

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2022
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OTX-TKI

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2022
Scientific Journal Publications

Hong T, Chang A, Maddess T, Provis J, Penfold P. Phase 1B study of the safety and tolerability of the mineralocorticoid fludrocortisone acetate in patients with geographical atrophy. BMJ Open Ophthalmology 2022;0:e001032. doi:10.1136/bmjophth-2022-001032

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2022
Scientific Journal Publications

Chen Y, Zhang T, Zeng S, Xu R, Jin K, Coorey NJ, Wang Y, Wang K, Lee S, Yam M, Zhu M, Chang A, Fan X, Zhang M, Du J, Gillies MC, Zhu L. Transketolase in human Müller cells is critical to resist light stress through the pentose phosphate and NRF2 pathways, Redox Biology, June 2022, 102379, ISSN 2213-2317,

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2022
Scientific Journal Publications

Hui V ,Szeto S.K.H., Tang F, Yang D, Chen H, Lai T, Rong A, Zhang S, Zhao P,  Ruamviboonsuk P, Lai CC, Chang A, Das D, Ohji M, Huang SS, Sivaprasad S, Wong TY, Lam DSC, Cheung CY. Optical Coherence Tomography Classification Systems for Diabetic Macular Edema and Their Associations With Visual Outcome and Treatment Responses – An Updated Review, Asia-Pacific Journal of Ophthalmology: June 2022 – Volume 11 – Issue 3 – p 247-25

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2022
Scientific Journal Publications

Cheung R, Ly A, Katalinic P, Coroneo MT, Chang A, Kalloniatis M, Madigan MC, Nivison-Smith L. Visualisation of peripheral retinal degenerations and anomalies with ocular imaging. Seminars in Ophthalmology. 2022 Mar 7. DOI: 10.1080/08820538.2022.2039222

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2022
Scientific Journal Publications

Eter N, Singh RP, Abreu F, Asik K, Basu K, Baumal C, Chang A, Csaky KG, Haskova Z, Lin H, Ruiz C Q, Ruamviboonsuk P, Silverman D, Wykoff CC, Willis JR. Yosemite And Rhine. Phase 3 Randomized Clinical Trials Of Faricimab For Diabetic Macular Edema: Study Design And Rationale. Ophthalmology Science. 2022 Mar;2(1):100111.

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2021
Scientific Journal Publications

Spooner KL, Fraser-Bell S, Hong T, Wong JG, Chang AA. Long-term outcomes of anti-VEGF treatment of retinal vein occlusion. Eye (Lond). 2021 Jun 11.

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2021
Scientific Journal Publications

Jhaveri, C., Wykoff, C.C., Khanani, A.M., Eandi, C.M., Chang, A., Guruprasad, B., Gedif, K.A. and Singer, M., 2021. Early Residual Fluid-free Status and Long-term BCVA outcomes: A Treatment Agnostic, Post-hoc Analysis of Pooled HAWK and HARRIER Data. American Journal of Ophthalmology.

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2021
Current Research Trials

Avonelle-X

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2021
Current Research Trials

Comino

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2021
Current Research Trials

Balaton

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2021
Scientific Journal Publications

Spooner K, Phan L, Cozzi M, Hong T, Staurenghi G, Chu E, Chang AA. Comparison between two multimodal imaging platforms: Nidek Mirante and Heidelberg Spectralis. Graefes Arch Clin Exp Ophthalmol. 2021 Jan 6. doi: 10.1007/s00417-020-05050-7. Epub ahead of print. PMID: 33409677.

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2021
Scientific Journal Publications

Broadhead GK, Hong T, Bahrami B, Flood V, Liew G, Chang AA. Diet and risk of visual impairment: a review of dietary factors and risk of common causes of visual impairment. Nutr Rev. 2021 May 12;79(6):636-650.

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2021
Scientific Journal Publications

Bowditch E, Chu E, Hong T, Chang AA. Treat and extend paradigm in management of neovascular age-related macular degeneration: current practice and future directions. Expert Review of Ophthalmology. 2021 May 26.

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2021
Scientific Journal Publications

Ogura Y, Jaffe GJ, Cheung CM, Kokame GT, Iida T, Takahashi K, Lee WK, Chang AA, Monés J, D’Souza D, Weissgerber G. Efficacy and safety of brolucizumab versus aflibercept in eyes with polypoidal choroidal vasculopathy in Japanese participants of HAWK. British Journal of Ophthalmology. 2021 Jul 21.

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2021
Scientific Journal Publications

Racic T, Chang A, Fernando N, Brandli A, Natoli R, Penfold P, Provis JM, Rutar M. Anti-inflammatory and neuroprotective properties of the corticosteroid fludrocortisone in retinal degeneration. Exp Eye Res. 2021 Sep 9:108765. doi: 10.1016/j.exer.2021.108765. Epub ahead of print. PMID: 34509498.

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2021
Scientific Journal Publications

Chaikitmongkol V, Sagong M, Lai TYY, Tan G.S, Fariza N, Ohji M, Mitchell P, Yang CH, Raumviboonsik P, Wong I, Sakamoto T, Rajendran A, Chen Y, Wong TY, Cheung CMG, Chang A, Koh A. Treat-and-extend regimens for the management of neovascular age-related macular degeneration and polypoidal choroidal vasculopathy: Consensus and recommendations from the Asia-Pacific Vitreo-Retina Society. APJO 2021 In press

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2021
Featured Publication

Comparison between two multimodal imaging platforms: Nidek Mirante and Heidelberg Spectralis

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Optical-coherence tomography angiography and ultrawide-field angiography findings in eyes with refractory macular edema secondary to retinal vein occlusion switched to aflibercept: A subanalysis from a 48-week prospective study. Taiwan J Ophthalmol. 2020 [Epub ahead of print]

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2020
Scientific Journal Publications

Ong EL, Spooner K, Hong T, Chang A. Brolucizumab: an evolution in treatment for neovascular age-related macular degeneration. Expert Review of Ophthalmology. 2020 Mar 3;15(2):71-81.

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2020
Scientific Journal Publications

Broadhead GK, Hong T, Chang AA. To Treat or Not to Treat: Management Options for Symptomatic Vitreous Floaters. The Asia-Pacific Journal of Ophthalmology. 2020 Mar 1;9(2):96-103.

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Effects of Switching to Aflibercept in Treatment Resistant Macular Edema Secondary to Retinal Vein Occlusion. Asia-Pacific Journal of Ophthalmology: January-February 2020 – Volume 9 – Issue 1 – p 48-53

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2020
Scientific Journal Publications

Kunimoto D, Yoon YH, Wykoff CC, Chang A, Khurana RN, Maturi RK, Agostini H, Souied E, Chow DR, Lotery AJ, Ohji M. Efficacy and Safety of Abicipar in Neovascular Age‐Related Macular Degeneration: 52-Week Results of Phase 3 Randomized Controlled Study. Ophthalmology. 2020 Apr 9.

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2020
Scientific Journal Publications

Spooner KL, Fraser-Bell S, Cozzi M, Staurenghi G, Invernizzi A, Monteduro D, Munk MR, Hong T, Chang AA. Macular Atrophy Incidence and Progression in Eyes with Neovascular Age-Related Macular Degeneration Treated with VEGF Inhibitors Using a Treat-and-Extend or a Pro-Re-Nata Regimen. Four Year Results of the MANEX Study. Ophthalmology. 2020 Jun 13.

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Effects of Switching to Aflibercept in Treatment Resistant Macular Edema Secondary to Retinal Vein Occlusion. Asia-pacific Journal of Ophthalmology (Philadelphia, Pa.). 2020 Jan;9(1):48.

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Effects of Switching to Aflibercept in Treatment Resistant Macular Edema Secondary to Retinal Vein Occlusion. Asia-pacific Journal of Ophthalmology (Philadelphia, Pa.). 2020 Jan;9(1):48.

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2020
Scientific Journal Publications

Kunimoto D, Yoon YH, Wykoff CC, Chang A, Khurana RN, Maturi RK, Agostini H, Souied E, Chow DR, Lotery AJ, Ohji M. Efficacy and Safety of Abicipar in Neovascular Age‐Related Macular Degeneration: 52-Week Results of Phase 3 Randomized Controlled Study. Ophthalmology. 2020 Apr 9.

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2020
Scientific Journal Publications

Spooner KL, Fraser-Bell S, Cozzi M, Staurenghi G, Invernizzi A, Monteduro D, Munk MR, Hong T, Chang AA. Macular Atrophy Incidence and Progression in Eyes with Neovascular Age-Related Macular Degeneration Treated with VEGF Inhibitors Using a Treat-and-Extend or a Pro-Re-Nata Regimen. Four Year Results of the MANEX Study. Ophthalmology. 2020 Jun 13.

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2020
Scientific Journal Publications

Broadhead GK, Hong T, Grigg JR, McCluskey P, Schlub TE, Spooner K, Chang AA. Does functional assessment predict everyday visual functioning? Visual function testing and quality of life in mild/moderate age-related macular degeneration. International Ophthalmology. 2020 Jul 14:1-9.

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2020
Scientific Journal Publications

Li Y, Alhendi A, Yeh M, Elahy M, Santiago F, Deshpande N, Wu B, Chan E, Inam S, Prado-Lourenco L, Marchang J, Joyce R, Wilkinson-White L, Fatery M, Zhu M, Adamson S, Barnat F, Viaud-Quentric K, Sockler J, Mackay J, Chang A, Mitchell P, Marcuccio S, Kachigian L. Thermostable small-molecule inhibitor of angiogenesis and vascular permeability that suppresses a pERK-FosB/ΔFosB–VCAM-1 axis. Sci Adv. 2020;6(31).

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2020
Current Research Trials

Canberra

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2020
Current Research Trials

Exonate

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2020
Current Research Trials

ISEE2008

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2020
Scientific Journal Publications

Spooner K, Fraser‐Bell S, Hong T, Chang A. Prospective study of aflibercept for the treatment of persistent macular oedema secondary to retinal vein occlusions in eyes not responsive to long‐term treatment with bevacizumab or ranibizumab. Clinical & Experimental Ophthalmology. 2020 Jan;48(1):53-60.

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Patient-reported outcomes from a phase IV study of aflibercept in patients with refractory retinal vein occlusions. Taiwan J Ophthalmol. 2020 [Epub ahead of print]

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Optical-coherence tomography angiography and ultrawide-field angiography findings in eyes with refractory macular edema secondary to retinal vein occlusion switched to aflibercept: A subanalysis from a 48-week prospective study. Taiwan J Ophthalmol. 2020 [Epub ahead of print]

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2020
Scientific Journal Publications

Ong EL, Spooner K, Hong T, Chang A. Brolucizumab: an evolution in treatment for neovascular age-related macular degeneration. Expert Review of Ophthalmology. 2020 Mar 3;15(2):71-81.

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Effects of Switching to Aflibercept in Treatment Resistant Macular Edema Secondary to Retinal Vein Occlusion. Asia-Pacific Journal of Ophthalmology: January-February 2020 – Volume 9 – Issue 1 – p 48-53

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2020
Scientific Journal Publications

Broadhead GK, Hong T, Chang AA. To Treat or Not to Treat: Management Options for Symptomatic Vitreous Floaters. The Asia-Pacific Journal of Ophthalmology. 2020 Mar 1;9(2):96-103.

Read more
2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Effects of Switching to Aflibercept in Treatment Resistant Macular Edema Secondary to Retinal Vein Occlusion. Asia-pacific Journal of Ophthalmology (Philadelphia, Pa.). 2020 Jan;9(1):48.

Read more
2020
Scientific Journal Publications

Kunimoto D, Yoon YH, Wykoff CC, Chang A, Khurana RN, Maturi RK, Agostini H, Souied E, Chow DR, Lotery AJ, Ohji M. Efficacy and Safety of Abicipar in Neovascular Age‐Related Macular Degeneration: 52-Week Results of Phase 3 Randomized Controlled Study. Ophthalmology. 2020 Apr 9.

Read more
2020
Scientific Journal Publications

Spooner KL, Fraser-Bell S, Cozzi M, Staurenghi G, Invernizzi A, Monteduro D, Munk MR, Hong T, Chang AA. Macular Atrophy Incidence and Progression in Eyes with Neovascular Age-Related Macular Degeneration Treated with VEGF Inhibitors Using a Treat-and-Extend or a Pro-Re-Nata Regimen. Four Year Results of the MANEX Study. Ophthalmology. 2020 Jun 13.

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2020
Scientific Journal Publications

Li Y, Alhendi A, Yeh M, Elahy M, Santiago F, Deshpande N, Wu B, Chan E, Inam S, Prado-Lourenco L, Marchang J, Joyce R, Wilkinson-White L, Fatery M, Zhu M, Adamson S, Barnat F, Viaud-Quentric K, Sockler J, Mackay J, Chang A, Mitchell P, Marcuccio S, Kachigian L. Thermostable small-molecule inhibitor of angiogenesis and vascular permeability that suppresses a pERK-FosB/ΔFosB–VCAM-1 axis. Sci Adv. 2020;6(31).

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2020
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Phan L, Wong JG, Chang A. Long-term Anti-Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration: The LATAR Study: Report 1: Ten-Year, Real-World Outcomes. Ophthalmol Retina. 2021 Jun;5(6):511-518. doi: 10.1016/j.oret.2020.09.019. Epub 2020 Sep 29.

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2020
Scientific Journal Publications

Ruamviboonsuk P, Lai TYY, Chang A, Lai CC, Mieler WF, Lam DSC; for Asia-Pacific Vitreo-Retina Society. Chloroquine and Hydroxychloroquine Retinal Toxicity Consideration in the Treatment of COVID-19. Asia Pac J Ophthalmol (Phila). 2020 Mar-Apr;9(2):85-87. doi: 10.1097/APO.0000000000000289. PMID: 32349115; PMCID: PMC7227199.

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2019
Scientific Journal Publications

Paul R, Simunovic M, Dawkins R, Bhullar G, Essex R, Chang A, Allen P. Early vitrectomy in endophthalmitis. In clinical and experimental ophthalmology 2019 Nov 1 (vol. 47, pp. 155-155). 111 river st, hoboken 07030-5774, nj usa: wiley.

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2019
Scientific Journal Publications

Bahrami B, Hong T, Peto T, Chang A. Ultra-Widefield Fluorescein Angiography as a Biomarker for Response to Switch in Therapy in Persistent DME. Ophthalmic Surgery, Lasers and Imaging Retina. 2019 Dec 27;50(12):771-8.

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2019
Scientific Journal Publications

Bahrami B, Hong T, Schlub T, Chang A. Aflibercept for persistent diabetic macular oedema: 48 week outcomes. Retina. 1 Jan 2019.

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2019
Scientific Journal Publications

Wan R, Hong T, Tariq Y, Chang A. Pharmacotherapy of vitreomacular traction. Curr Pharm Des 2019.

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2019
Scientific Journal Publications

Spooner K, Hong T, Fraser-Bell S, Chang A. Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central Retinal Vein Occlusions: A Systematic Review and Meta-Analysis. Asia Pac J Ophthalmol (Phila). 2019 May-Jun;8(3):236-246.

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2019
Current Research Trials

Lucerne

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2019
Scientific Journal Publications

Ong AP, Angbue Te N, Zagora SL, Symes RJ, Yates W, Chang AA, McCluskey PJ, Simunovic MP. Post‐surgical versus post‐intravitreal injection endophthalmitis: changing patterns in causative flora. Clinical & experimental ophthalmology. 2019 Jan;47(1):57-62.

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2019
Scientific Journal Publications

Bahrami B, Hong T, Schlub TE, Chang AA. Aflibercept For Persistent Diabetic Macular Edema: Forty-Eight–Week Outcomes. Retina. 2019 Jan 1;39(1):61-8.

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2019
Scientific Journal Publications

Ho IV, Fernandez-Sanz G, Levasseur S, Ting E, Liew G, Playfair J, Downie J, Gorbatov M, Hunyor AP, Chang AA. Early pars plana vitrectomy for treatment of acute infective endophthalmitis. The Asia-Pacific Journal of Ophthalmology. 2019 Jan 1;8(1):3-7.

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2019
Scientific Journal Publications

Broadhead GK, Grigg JR, McCluskey P, Hong T, Schlub TE, Chang AA. Saffron therapy for the treatment of mild/moderate age-related macular degeneration: a randomised clinical trial. Graefe’s Archive for Clinical and Experimental Ophthalmology. 2019 Jan 28;257(1):31-40.

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2019
Scientific Journal Publications

Spooner K, Hong T, Bahrami B, Chang A. A meta‐analysis of patients with treatment‐resistant macular oedema secondary to retinal vein occlusions following switching to aflibercept. Acta ophthalmologica. 2019 Feb;97(1):15-23.

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2019
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang AA. Five-year outcomes of retinal vein occlusion treated with vascular endothelial growth factor inhibitors. BMJ open ophthalmology. 2019 Mar 1;4(1):e000249.

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2019
Scientific Journal Publications

Guymer RH, Markey CM, McAllister IL, Gillies MC, Hunyor AP, Arnold JJ, Chang A, Syed A, Broadhead G, Pham T, Hong T. Tolerating subretinal fluid in neovascular age-related macular degeneration treated with ranibizumab using a treat-and-extend regimen: FLUID study 24-month results. Ophthalmology. 2019 May 1;126(5):723-34.

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2019
Scientific Journal Publications

Duerr ER, Chang A, Venkateswaran N, Goldhardt R, Levitt RC, Gregori NZ, Sarantopoulos CD, Galor A. Resolution of pain with periocular injections in a patient with a 7-year history of chronic ocular pain. American journal of ophthalmology case reports. 2019 Jun 1;14:35-8.

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2019
Scientific Journal Publications

Spooner K, Hong T, Nair R, Chow NC, Broadhead GK, Wijeyakumar W, Chang AA. Long‐term outcomes of switching to aflibercept for treatment‐resistant neovascular age‐related macular degeneration. Acta ophthalmologica. 2019 Aug;97(5):e706-12.

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2019
Scientific Journal Publications

Wan R, Chang A. Optic disc pit maculopathy: a review of diagnosis and treatment. Clinical and Experimental Optometry. 2019 Aug 22.

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2019
Scientific Journal Publications

Bahrami B, Shen W, Zhu L, Zhang T, Chang A, Gillies MC. Effects of VEGF inhibitors on human retinal pigment epithelium under high glucose and hypoxia. Clinical & experimental ophthalmology. 2019 Nov;47(8):1074-81.

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2019
Scientific Journal Publications

Hong T, Phan L, Spooner K, Chang A. Comparing Morphological Outcomes Between Ranibizumab And Afliberept For The Treatment Of Neovascular Age-Related Macular Degeneration. In Clinical And Experimental Ophthalmology 2019 Nov 1 (Vol. 47, Pp. 156-157). 111 River St, Hoboken 07030-5774, Nj Usa: Wiley.

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2019
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Aflibercept In Macular Oedema Secondary To Retinal Vein Occlusion Refractory To Previous Bevacizumab Or Ranibizumab: 48 Week Outcomes. In Clinical And Experimental Ophthalmology 2019 Nov 1 (Vol. 47, Pp. 155-156). 111 River St, Hoboken 07030-5774, Nj Usa: Wiley.

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2019
Scientific Journal Publications

Spooner K, Fraser-Bell S, Cozzi M, Monteduro D, Luo K, Hong T, Munk M, Invernizzi A, Staurenghi G, Chang A. Comparison of macular atrophy in eyes with neovascular age-related macular degeneration treated with VEGF inhibitors using a treat-and-extend or pro re nata regimen: 4-year results of the MANEX study. In Clinical And Experimental Ophthalmology 2019 Nov 1 (Vol. 47, Pp. 63-63). 111 River St, Hoboken 07030-5774, Nj Usa: Wiley.

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2019
Scientific Journal Publications

Ong E, Spooner K, Hong T, Chang A. Longitudinal retinal ganglion cell thickness change in patients receiving intravitreal anti-vascular endothelial growth factor for neovascular age-related macular degeneration. In Clinical And Experimental Ophthalmology 2019 Nov 1 (vol. 47, pp. 159-159). 111 river st, hoboken 07030-5774, nj usa: wiley.

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2019
Scientific Journal Publications

Paul R, Simunovic M, Dawkins R, Bhullar G, Essex R, Chang A, Allen P. Early vitrectomy in endophthalmitis. In clinical and experimental ophthalmology 2019 Nov 1 (vol. 47, pp. 155-155). 111 river st, hoboken 07030-5774, nj usa: wiley.

Read more
2019
Scientific Journal Publications

Spooner K, Hong T, Fraser-Bell S, Chang A. Current outcomes of Anti-VEGF therapy in the treatment of macular oedema secondary to branch retinal vein occlusions: A meta-analysis. Ophthalmologica 2019.

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2019
Scientific Journal Publications

Ho I, Fernandez G, Levasseur S, Ting E, Liew G, Playfair J, Downie J, Gorbatov M, Hunyor A, Chang A. Early Pars plana vitrectomy for treatment of acute infective endophthalmitis. Asia Pacific Journal of Ophthalmology. 2019.

Read more
2019
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. 5 year outcomes of retinal vein occlusion treated with vascular endothelial derived growth factor inhibitors. BMJ ophthal 2019.

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2019
Scientific Journal Publications

Broadhead G, Grigg J, McCluskey P, Hong T, Schlub T, Chang A. Saffron therapy for the treatment of mild/moderate age-related macular degeneration: a randomised clinical trial. Graefe’s Archive for Clinical and Experimental Ophthalmology. 28 Jan 2019.

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2019
Scientific Journal Publications

Spooner K, Hong T, Nair R, Chow N, Broadhead G, Wijeyakumar W, Chang A. Long‐term outcomes of switching to aflibercept for treatment‐resistant neovascular age‐related macular degeneration. Acta ophthalmologica. 11 Feb 2019.

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2019
Scientific Journal Publications

Spooner K, Hong T, Bahrami B, Chang A. A meta-analysis of patients with treatment-resistant macular oedema secondary to retinal vein occlusions following switching to aflibercept. Acta Ophthalmol. 2019 Feb;97(1):15-23.

Read more
2019
Scientific Journal Publications

Bahrami B, Hong T, Peto T, Chang A. Ultra-Widefield Fluorescein Angiography as a Biomarker for Response to Switch in Therapy in Persistent DME. Ophthalmic Surgery, Lasers and Imaging Retina. 2019 Dec 27;50(12):771-8.

Read more
2019
Scientific Journal Publications

Bahrami B, Hong T, Schlub T, Chang A. Aflibercept for persistent diabetic macular oedema: 48 week outcomes. Retina. 1 Jan 2019.

Read more
2019
Scientific Journal Publications

Spooner K, Fraser-Bell S, Hong T, Chang A. Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Oedema Secondary to Branch Retinal Vein Occlusions: A Meta-Analysis Ophthalmogica. 2019

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2019
Scientific Journal Publications

Spooner K, Hong T, Fraser-Bell S, Chang A. Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central Retinal Vein Occlusions: A Systematic Review and Meta-Analysis. Asia Pac J Ophthalmol (Phila). 2019 May-Jun;8(3):236-246.

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2019
Scientific Journal Publications

Spooner KL, Guinan G, Koller S, Hong T, Chang AA. Burden of Treatment Among Patients Undergoing Intravitreal Injections For Diabetic Macular Oedema In Australia. Diabetes Metab Syndr Obes. 2019 Sep 19;12:1913-1921.

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2019
Scientific Journal Publications

Spooner K, Hong T, Fraser-Bell S, Chang A. Current Outcomes of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Central Retinal Vein Occlusions: A Systematic Review and Meta-Analysis. Asia Pac J Ophthalmol (Phila). 2019 May-Jun;8(3):236-246.

Read more
2019
Scientific Journal Publications

Spooner K, Fraser‐Bell S, Hong T, Chang A. Prospective study of aflibercept for the treatment of persistent macular oedema secondary to retinal vein occlusions in eyes not responsive to long‐term treatment with bevacizumab or ranibizumab. Clinical & Experimental Ophthalmology. 2019 Sep;48(1):53-60.

Read more
2019
Scientific Journal Publications

Wan R, Chang A. Optic disc pit maculopathy: a review of diagnosis and treatment. Clinical and Experimental Optometry. 2019 Aug 22.

Read more
2019
Scientific Journal Publications

Broadhead G, Grigg J, McCluskey P, Hong T, Schlub T, Chang A. Saffron therapy for the treatment of mild/moderate age-related macular degeneration: a randomised clinical trial. Graefe’s Archive for Clinical and Experimental Ophthalmology. 28 Jan 2019

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2018
Current Research Trials

Derby

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2018
Current Research Trials

IONIS

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2018
Scientific Journal Publications

Chow N, Hong T, Chang A. Multimodal imaging of macular subretinal deposits following intravitreal ocriplasmin injection. AJO Case Reports 2018 2018;9:80-84

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2018
Scientific Journal Publications

Ong PC, Te NA, Zagora S, Symes R, Yates Y, Chang A, McCluskey P, Simunovic M. Post-surgical versus post-intravitreal injection endophthalmitis: changing patterns in causative flora. Clinical & Experimental Ophthalmology (In press)

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2018
Scientific Journal Publications

Bahrami B, Hong T, Schlub T, Chang A. Aflibercept for persistent diabetic macular edema: 48 week outcomes. Retina. (In press)

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2018
Scientific Journal Publications

Spooner K, Bahrami B, Hong T, Chang A. A Meta-Analysis of Patients with Treatment Resistant Macular Oedema Secondary to Retinal Vein Occlusions following Switching to Aflibercept. Acta Ophthalmologica (In press)

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2018
Scientific Journal Publications

Chhablnai J, Shaikh A, Goud A, Kawasaki R, Kwon OW, Chang A, Lam D, Das T,  Asia Pacific-Technology and Trend Survey 2016-17. Asia Pacific Journal of Ophthalmology (Accepted for publication)

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2017
Scientific Journal Publications

Zhu M Wijeyakumar W, Syed A, Joachim N, Hong T, Broadhead G, Li H, Luo K, Chang A, Vision-related quality of life: 12 month aflibercept treatment in patients with treatment-resistant neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2017 Mar;255(3):475-484.

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2017
Scientific Journal Publications

Bahrami B, Hong T, Zhu M, Schlub TE, Chang A. Switching therapy from bevacizumab to aflibercept for the management of persistent diabetic macular edema. Graefes Arch Clin Exp Ophthalmol. Graefes Arch Clin Exp Ophthalmol. 2017 Jun;255(6):1133-1140

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2017
Scientific Journal Publications

Spooner K, Hong T, Wijeyakumar W, Chang AA. Switching to aflibercept among patients with treatment-resistant neovascular age-related macular degeneration: a systematic review with meta-analysis. Clinical Ophthalmology 2017,11:161-177

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2017
Scientific Journal Publications

Nair R, Chang A. Challenges in the treatment of age-related macular degeneration. Medicine Today. 2017; 18(2): 400-400

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2017
Scientific Journal Publications

Bahrami B, Ewe S, Hong T, Zhu M, Ong G, Luo K, Chang A. Influence of retinal pathology on the reliability of macular thickness measurement: a comparison between optical coherence tomography devices. Ophthalmic Surg Lasers Imaging Retina. 2017 Apr 1;48(4):319-325.

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2017
Scientific Journal Publications

Chew J, Zhu M, Broadhead G, Luo K, Hong T, Chang A. Bilateral neovascular age-related macular degeneration: Comparisons between first and second eyes. Ophthalmologica. 2017;238(1-2):23-30.

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2017
Scientific Journal Publications

Bahrami B, Hong T, Zhu M, Sclubb T, Chang A. Switching therapy from bevacizumab to aflibercept for the management of persistent diabetic macular edema. Graefes Arch Clin Exp Ophthalmol. 2017 Jul;255(7):1453-1454.

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2017
Current Research Trials

EC-FCA-001

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2017
Scientific Journal Publications

Broadhead GK, Hong T, McCluskey P, Grigg JR, Schlub TE, Chang AA. Choroidal thickness and microperimetry sensitivity in age-related macular degeneration. Ophthalmic Res. 2017;58(1):27-34.

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2017
Scientific Journal Publications

Bahrami B, Hong T, Gilles MC, Chang A. Anti-VEGF therapy for diabetic eye disease. Asia Pac J Ophthalmol (Phila). 2017 Oct 26. doi: 10.22608/APO.2017350. [Epub ahead of print]

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2017
Scientific Journal Publications

Chang A, Chan P, Schlottman. Latest developments in age-related macular degeneration. Asia Pac J Ophthalmol. 2017 [Epub ahead of print]

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2016
Scientific Journal Publications

Chang A, Broadhead G, Hong T, Joachim N, Syed A, Schlub T, Toth L, Peto T, Zhu M. Intravitreal Aflibercept for Treatment-Resistant Neovascular Age-Related Macular Degeneration: 12-Month Safety and Efficacy Outcomes. Ophthalmic Research 2016;55: 84–90

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2016
Scientific Journal Publications

Ewe S, Jamieson R, Chang A. Masquerade macular exudation in Mallatia Leventinese. Can J Ophthalmol 2016;51: e24–e27

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2016
Scientific Journal Publications

G K Broadhead J R Grigg P McCluskeyM KorsakovaA A Chang. Bevacizumab for choroidal neovascularisation in enhanced S-cone syndrome.Documenta Ophthalmologica 2016; 133(2): 139-143

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2016
Scientific Journal Publications

Bahrami B, Zhu M, Hong T, Chang A. Diabetic macular oedema: pathophysiology, management challenges and treatment resistance. Diabetologia 2016, 59(8): 1594-608

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2016
Scientific Journal Publications

Powner M, Sim D , Zhu M, Nobre-Cardoso J, Jones R, Syed A, Chang A , Keane P, Tufail A, Egan C. Evaluation of non-perfused retinal vessels in ischemic retinopathy. IOVS 2016, 1;57(11) 5031-5037

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2015
Scientific Journal Publications

Broadhead GK, T Hong, Zhu M, Schulb T, Wijeyakumar W, Chang AA. Response of Pigment Epithelial Detachments to Intravitreal Aflibercept among Patients with Treatment-Resistant Neovascular Age-Related Macular Degeneration. Retina, 2015; 35(5): 975-81

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2015
Scientific Journal Publications

Staffieri SE, Rose L, Chang A, De Roach JN, McLaren TL, Mackey DA, Hewitt AW, Lamey TM. Clinical and molecular characterisation of females affected by X-linked retinoschisis. Clinical Experimental Ophthalmology 2015, 43(7):643-7

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2015
Scientific Journal Publications

Broadhead GK, Grigg J, Chang AA, McCluskey P. Dietary Modification and Supplementation for the Treatment of Age-Related Macular Degeneration. Nutrition Reviews 2015; 73(7): 448-62

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2015
Scientific Journal Publications

Broadhead GK, Chang AA. Intravitreal aflibercept for choroidal neovascularization complicating chronic central serous retinopathy. Graefes Archive for clinical and experimental ophthalmology 2015; 253: 979-981

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2015
Scientific Journal Publications

Chang AA, Hong T, Ewe S, Badami B. The Role of Aflibercept in the management of Diabetic Macular Edema. Drug Design, Development and Therapy. 2015, 6:9:4389-96

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2015
Scientific Journal Publications

Chang A, Li H, Broadhead G, Luo K, Zhu M, Safety and Efficacy of Intravitreal Preservative-free Triamcinolone Acetonide (Triesence) for Macular Edema. Journal of Ocular Pharmacology and Therapeutics. 2015:31(9):563-9

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2014
Scientific Journal Publications

Zhu M, Chew J, Broadhead G, Luo K, Joachim N, Hong T, Syed A, Chang AA. Intravitreal Ranibizumab for neovascular age-related macular degeneration in clinical practice: 5 year treatment outcomes. Graefes Archive for clinical and experimental ophthalmology, 2014, 253(8).

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2014
Scientific Journal Publications

Chang AA, Li H, Broadhead GK, Hong T, Schlub TE, Wijeyakumar W, Zhu M. Intravitreal Aflibercept for Treatment-Resistant Neovascular Age-related macular degeneration. Ophthalmology, 2014; 121(1): 188-192.

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2014
Scientific Journal Publications

Broadhead G and Chang AA. Acetazolamide for Cystoid Macular Oedema in Bietti Crystalline Retinal Dystrophy. Korean J Ophthalmol 2014; 28(2):189-191.

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2014
Scientific Journal Publications

Broadhead G, Hong T, Chang AA. Treating the Untreatable Patient: Current Options for the Management of Treatment-Resistant Neovascular Age-Related Macular Degeneration. Acta Ophthalmologica 2014; 92(8):713-23.

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2014
Scientific Journal Publications

Broadhead G, Grigg J, Chang A, McCluskey P. Efficacy and Safety of Saffron Supplementation: Current Clinical Findings. Critical Reviews in Food Science and Nutrition. 2016, 9:56(16) 2767-76

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2014
Scientific Journal Publications

Rush R, Simunovic M, Sheth S, Chang A Hunyor A. 23-Gauge Pars Plana Vitrectomy Versus Scleral Buckling Versus Combined Pars Plana Vitrectomy–Scleral Buckling for Medium-Complexity Retinal Detachment Repair. Asia-Pacific Journal of Ophthalmology 2014; 3: 215-219

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2013
Scientific Journal Publications

Chang A. Editorial. Is there one less hurdle for patients undergoing macular hole surgery? Asia-Pacific Journal of Ophthalmology 2013. 2(1):1-2

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2013
Scientific Journal Publications

Wang YD and Chang A. Clinical features and PDT effect of patients with CCSC. International Eye Science 2013. 13:3. 522-526

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2013
Scientific Journal Publications

Chui J, Herkes G, Chang A. Management of fingolimod associated macular edema, JAMA Ophthalmology 2013; 131(5): 694-6

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2013
Scientific Journal Publications

Broadhead G and Chang A. Choroidal Neovascularisation in Acquired Partial Lipodystrophy. European journal Ophthalmology 2013; 23(3): 439-41

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2012
Scientific Journal Publications

Simunovic MP, Rush RP, Hunyor AP, Chang AA. Endophthalmitis following intravitreal injection versus endophthalmitis following cataract surgery: clinical features, causative organisms and post-treatment outcomes. British Journal Ophthalmology. 2012; 96 (6):862-6

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2012
Scientific Journal Publications

Broadhead, GK, Chang, AA, and McCluskey, P, Genetics in Age-Related Macular Degeneration: Current Research and Implications for Future Treatment, Asia Pacific Journal Ophthalmology, 2012; 1(5): p. 312-18

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